Matlacha Isles is located in Florida. Matlacha Isles, Florida has a population of101,539.
The median household income in Matlacha Isles, Florida is $64,244. The median household income for the surrounding county is $62,055 compared to the national median of $66,222. The median age of people living in Matlacha Isles is 44.7 years.
The average high temperature in July is 91.7 degrees, with an average low temperature in January of 54.5 degrees. The annual precipitation is 54.19.